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Journal articles
Protein Nanocapsules Produced by Nanoprecipitation of Designed Suckerin-Silk Fusion Proteins
Abstract : Herein, we report on the precise design of a modular fusion protein amenable to the construction of nanocapsules by nanoprecipitation. The central squid suckerin-derived peptide block provides structural stability, whereas both termini from silk fibroins make the modular protein highly soluble at physiological pH, a critical requirement for the nanoprecipitation process. With this molecular design, nanocapsules consisting of suckerin-silk fusion protein shells and hexadecane or miglyol cores with sizes in the range 190-250 nm are straightforwardly built.
Keywords :
Nanocarriers
Spider silk
https://hal-insa-lyon.archives-ouvertes.fr/hal-03264411
Contributor : Direction de la Recherche Insa Lyon <>
Submitted on : Friday, June 18, 2021 - 11:01:33 AM
Last modification on : Saturday, June 19, 2021 - 4:06:30 AM
Contributor : Direction de la Recherche Insa Lyon <>
Submitted on : Friday, June 18, 2021 - 11:01:33 AM
Last modification on : Saturday, June 19, 2021 - 4:06:30 AM